SciPinion Launches AI Tool to Benchmark New Ingredients Against FDA-Cleared GRAS Precedents

US risk assessment firm SciPinion has launched SciBridge Safety Suite, an AI-assisted software that compares new food ingredients to substances reviewed by the FDA's GRAS notice program. The tool aims to help companies prepare for a proposed rule that would require GRAS notification. SciBridge can generate a full similarity report against an FDA-cleared precedent in about ten minutes, saving time and costs compared to a ground-up GRAS review.

The proposed rule includes exemptions for certain ingredient categories already covered by an FDA "no questions" letter. SciPinion sees this as an exemption route for ingredients that match existing precedents. The software, based on the FDA's GRAS notice inventory, has three components and can be accessed through subscription or professional services. The tool is designed to streamline data review processes and help companies transitioning from self-affirmed to notified status, providing a valuable resource for the food industry and FDA to enhance public health protection.