California-based startup Fermeate has closed a $2 million seed funding round to further develop its optogenetics platform for controlling gene expression in microbial cells during fermentation using light signals. The technology inserts light-sensitive proteins into microbial strains, allowing manufacturers to activate or deactivate specific genes in real time. By targeting which enzymes or proteins are regulated, the system achieves up to 200% increase in protein production within six months and addresses genetic drift issues that can diminish microbial efficiency during production runs.

The platform, which is compatible with existing infrastructure, connects externally to fermentation tanks via a light-delivery device, eliminating the need for new bioreactors. Utilizing AI and machine learning, optimal light patterns are determined to sustain output and improve protein synthesis while reducing costs and increasing efficiency. Fermeate is currently offering paid pilots to generate revenue and exploring long-term commercial models to further advance the bioeconomy through efficient biomanufacturing processes.